The entry criteria included (1) anisometropia of 0.50 diopters (D) or more of the spherical equivalent and/or a 1.50-D or more difference between the eyes in astigmati; (2) VA in the amblyopic eye of a 0.3-0.8 logMAR (equivalent to 20/40-20/125) and VA in the sound eye of 0.1 logMAR or more (equivalent to 20/25); (3) an interocular VA difference of 2 logMAR lines or more; (4) a myopic spherical equivalent of no more than –6.00 D in the amblyopic eye; (5) no measurable heterotropia in primary gaze at distance or near fixation with spectacles or no documented history of strabius; (6) no other ocular cause for reduced acuity; and (7) no prior treatment for amblyopia except for spectacle use. The spectacles should have been worn until VA was stabilized (VA improved by <1 line compared with the previous visit at least 5 weeks earlier). Participants who showed stabilization within 12 weeks prior to the study-specified screening visit were instructed to continue wearing spectacles until after 12 weeks.
