求助几句翻译

1guidance for the work-up and diagnosis of spatially limited NMO spectrum disorders is provided by the task force

2the task force suggests concepts for treatment of acute exacerbations and attack prevention based on expert opinion.

3that further clinical and histopathological studies changed the concept and place of NMO within the expanding range of autoimmune disorders of the CNS

4The period for eligible articles ranged from 1965 to September 2009, and following suggestions from the reviewers also individual articles beyond this period

5NMO primarily affects non-whites and populations with a minor European contribution to their genetic composition

6Predictors of a recurrent course were a longer interattack interval between the first two clinical episodes,older age at onset, female gender and less severe motor impairment at the sentinel myelitis event

nmo ？I do not known

引用

引用第1楼lilimailfish于2010-10-27 22:06发表的  :
nmo ？I do not known

视神经脊髓炎

这几个句子蛮有难度咧，等高手吧

NMO spectrum disorders 视神经脊髓炎谱系障碍？

引用

引用第4楼xaken于2010-10-29 21:38发表的  :
NMO spectrum disorders 视神经脊髓炎谱系障碍？

对！
好久不见了

7Repeated NMO attacks are the main cause of accumulation of neurological impairment, whereas permanent disability in MS is primarily a feature of secondary progression

8A history of other autoimmune diseases, higher attack frequency during the first 2 years of disease and better motor recovery following the index myelitis event were associated with increased risk of fatality in recurrent NMO

9However, normal appearances or shorter lesions can be found very early during relapse or in residual atrophic stage

10In a study on LETM relapses in NMO

11fluoroimmunoprecipitation assays

12A French study using IIF did not report differences with regard to age and onset of disease,

13presence of NMO-IgG was associated with a worse course

14Detection of NMO-IgG was also associated with a higher probability for >3 periventricular lesions and localization within the deep white matter

15 at the nadir of exacerbations

16A French NMO study reported that the presence of NMO-IgG was linked to HLA-DRB1*01*03 (majority DR3)

17AQP4 antibodies in spatially limited syndromes

18 importantly appear to predict outcome in terms of conversion to NMO

19 In a series of three rapidly recurring LETM patients, AQP4 antibodies could not be detected in serum, but in CSF (class IV), confirming the diagnosis of a spatially limited NMO spectrum disorder and mandating initiation of immunosuppressive treatment

20All major criteria are required, but may be separated by an unspecified interval

21Non-specific brain T2-signal abnormalities not satisfying the Barkhof criteria for dissemination in space used in the revised McDonald criteria

22‘linear’ periventricular/corpus callosum signal abnormality, but not ovoid, not extending into the parenchyma of the cerebral hemispheres in Dawson finger configuration.