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Total Synthesis of (-)-Okilactomycin
Amos B. ith, III*, Kallol Basu, and Todd Bosanac
Isolation :
Isolated by the Imai and co-workers in 1987 from a bioactive filtrate Streptomyces griseoflavus
Bioactivity:
(+)-okilactomycin exhibits in vitro cytotoxicity against the human cell lines P388 (IC50 =0.09μg/mL)and lymphoid leukemia L1210(IC50 =0.037μg/mL)
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