| hf6391964 |
2010-10-12 07:25 |
Various aliphatic and aromatic dimethyl and diethyl acetals
and ketals were found to hydrolyse in essentially quantitative
yield when heated to 80 ◦C in neat water or aqueous
medium without a catalyst or any other additive, while
cyclic acetals were stable under these conditions. Selective
deprotection is possible when both types of acetal are
present.
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