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 Molecules and Medicine

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Molecules and Medicine
By E. J. Corey, László Kürti, Barbara Czakó

* Publisher: Wiley
* Number Of Pages: 272
* Publication Date: 2007-08-31
* IN-10 / ASIN: 0470227494
* IN-13 / EAN: 9780470227497

Product Description:

Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

PART I. INTRODUCTION.

UNDERSTANDING STRUCTURAL DIAGRAMS OF ORGANIC MOLECULES.
SOME COMMON MOLECULES.
PROTEINS AND THREE-DIMENSIONAL PROTEIN STRUCTURE.
SOME OF THE PROTEIN STRUCTURES THAT APPEAR IN THIS BOOK.
PART II. INFLAMMATORY, CARDIOVASCULAR AND METABOLIC DISEASES.
ANTI-INFLAMMATORY AGENTS.
Acetylsalicylic acid Aspirin™).
Naproxen (Aleve™).
How Do Anti-Inflammatory Drugs Work?
Other Eicosanoids in Inflammation.
An Overview of Inflammation.
Celecoxib (Celebrex™).
Prednisone (Deltasone™).
Methotrexate (Trexall™).
Allopurinol (Zyloprim™).

ANTIASTHMATIC AND ANTIALLERGIC AGENTS.
Salmeterol (Serevent™).
Fluticasone Propionate (Flovent™).
Montelukast Sodium (Singulair™).
Tiotropium Bromide (Spiriva™).
Lortadine (Claritin™).
TYPE 2 DIABETES.
An Overview of Metabolic Syndrome.
ANTIDIABETIC AND CHOLESTEROL-LOWERING AGENTS.
Metformin (Glucophage™).
Glipizide (Glucotrol™).
Pioglitazone (Actos™.
Sitagliptin (Januvia™.
Atorvastatin (Lipitor™.
Ezetimibe (Zetia™.
CARDIOVASCULAR AGENTS.
Atenolol (Tenormin™.
Enalapril (Vasotec™.
Candesartan Cilexetil (Atacand™.
Aliskiren (Tekturna™.
Amlodipine (Norvasc™.
Nitroglycerin.
Clopidogrel Bisulfate (Plavix™.
Digoxin (Lanoxin™.

RECEPTORS AND SIGNALING.
Information Flow into the Cell by Chemical Signaling.

REFERENCES FOR PART II.

PART III. REPRODUCTIVE MEDICINE.

Oral Contraceptives.
.
Mifepristone (Mifeprex™.
Oxytocin (Oxytocin™.
Sildenafil (Viagra™.
OSTEOPOROSIS.
Some Aspects of Osteoporosis.
Alendronate (Fosamax™.
Calcitriol (Rocaltrol™.
Raloxifene (Evista™.
Teriparatide (Forteo™.
GLAUCOMA AND ANTIULCER AGENTS.
Latanoprost (Xalatan™.
Ranitidine (Zantac™.
Omeprazole (Prilosec™.

REFERENCES FOR PART III.

PART IV. AUTOIMMUNE DISEASE AND ORGAN TRANSPLANT.

A Brief Survey of the Immune System.
IMMUNOSUPPRESSIVE AGENTS.
Azathioprine (Imuran™.
Mycophenolate Mofetil (CellCept™.
Cyclosporin (Neoral™.
Tacrolimus (Prograf™.
FTY720 (Fingolimod).
INFECTIOUS DISEASES.
ANTIBIOTICS.
Amoxicillin (Amoxil™.
Cefaclor (Ceclor™.
Doxycycline (Vibramycin™.
Azithromycin (Zithromax™.
Ciprofloxacin (Cipro™.
Trimethoprim (Triprim™.
Amikacin (Amikin™.
Vancomycin (Vancocin™.
Linezolid (Zyvox™.
Isoniazid (Laniazid™.
Ancillary Antibiotics.
Drug Resistance.
ANTIVIRAL AGENTS.
On Viruses and Viral Diseases.
Acyclovir (Zovirax™.
Ribavirin (Virazole™.
Oseltamivir (Tamiflu™.
Zidovudine (Retrovir, AZT™.
Zalcitabine (Hivid™.
Nevirapine (Viramune™.
Efavirenz (Sustiva™.
Lopinavir + Ritonavir (Kaletra™.
UK427857 (Maraviroc).

ANTIFUNGAL AGENTS.

Amphotericin (Fungizone™.
Fluconazole (Diflucan™.
Caspofungin (Cancidas™.
Terbinafine (Lamisil™.

ANTIMALARIAL AND ANTIPARASITIC AGENTS.

Parasitic Diseases: A Focus on Malaria.
Chloroquine (Aralen™.
Artemether + Lumefantrine (CoArtem™.
Atovaquone + Proguanil (Malarone™.
Miltefosine (Impavido™.
Nitazoxanide (Alinia™.
Ivermectin (Stromectol™.

REFERENCES FOR PART IV.

PART V. MALIGNANT DISEASE.

An Overview of Cancer.
Capecitabine (Xeloda™.
Carboplatin (Paraplatin™.
Vinblastine (Velban™.
Paclitaxel (Taxol™.
Cyclophosphamide (Cytoxan™.
(Nolvadex™.
Irinotecan (Camptosar™.
Bleomycin (Blenoxane™.
Imatinib (Gleevec™.
Sunitinib (Sutent™.
Bortezomib (Velcade™.
Ancillary Anticancer Agents.

REFERENCES FOR PART V.

PART VI. DRUGS ACTING ON THE NERVOUS SYSTEM.

PAIN AND GESIA.

Lidocaine (Xylocaine™.
(Avinza™.
Acetaminophen (Tylenol™.
Fentanyl (Duragesic™.
Sodium Thiopental (Sodium Pentothal™.
Gabapentin (Neurontin™.
Diazepam (Valium™.
Sumatriptan (Imitrex™.

HYPNOTICS (INSOMNIA) AND ANTIOKING.

Zolpidem (Ambien™.
Ramelteon (Rozerem™.
Varenicline (Chantix™.
The Brain, Neurotranission and Molecular Neurotranitters.

NEURODEGENERATIVE AND PSYCHIATRIC DISEASES.

Levodopa (Larodopa™.
Donepezil (Aricept™.
ANTIEPILEPTIC AGENTS.
ANTIANXIETY AGENTS.
ANTIDEPRESSANTS.
ANTIPSYCHOTICS.
REFERENCES FOR PART VI.
GLOSSARY.
INDEX.



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