由辉瑞公司的科学家介绍了连续反应在药物合成的应用
连续反应具有以下特点
high control of the reaction variables, which can translate into higher product
quality; increased safety; possibility of reactions at high temperature and pressure (Process
Intensification); possibility of automation; reduced manual handling; easier reproducibility; flexibility of
the production volume; possibility of in-line purification techniques and reaction telescoping; increased
contact surface between phases for bi and triphasic systems; bigger temporary catalyst/substrate ratio in
heterogeneously catalysed reactions,
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